Chronic periodontitis patients SRP,
Conditions
Interventions
Non-
surgical periodontal therapy (SRP) supported with probiotic(l.reuteri containing lozenges) supplement,Non-
surgical periodontal therapy(SRP)+xylitol containing placebo tablets
Active Comparator Other,Placebo Comparator Other
Hare Gursoy,Hare Gursoy
Sponsors
BioGaia,but the company was not involved in the data management
Eligibility
Sex/Gender
All
Age
35 Years to 50 Years
Inclusion criteria
Inclusion criteria: Chronic periodontitis patients with radiographically detected horizontal bone loss (Armitage 1999), the presence of at least 2 teeth with an approximal site each with a PD of 5-7 mm and a GI of ≥2 in each quadrant,
Exclusion criteria
Exclusion criteria: Periodontal or antimicrobial treatment within the prior 6 months, systemic disease, history of smoking, pregnancy, use of probiotic supplements, or a history of adverse reactions to lactose or fermented milk products.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing depth reduction and attachment gain Baseline, days 21,90,180 and 360 Periodontal probe | — |
Secondary
| Measure | Time frame |
|---|---|
| Plaque index Baseline, days 21,90,180 and 360 Periodontal probe,gingival index and bleeding on probing Baseline, days 21,90,180 and 360 Periodontal probe | — |
Countries
TURKEY
Contacts
Public ContactHare Gursoy
NONE
Outcome results
None listed