Effect of using positive end-expiratory pressure during positive-pressure ventilation in neonatal resuscitation to oxygenation in low birth weight infants, a pilot -study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20141009001

Enrollment

Registered

2014-10-09

Start date

2014-10-12

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Very low birthweight (VLBW) infants who require positive-pressure ventilation at birth. very low birthweight infants positive end-expiratory pressure positve-pressure ventilation

Interventions

expiratory pressure(PEEP) of 0 cmH2O during positve&#45

pressure ventilation(PPV).

Active Comparator Procedure/Surgery,Placebo Comparator Biological/Vaccine

"PEEP" group,"No PEEP" group

Using positive end&#45

expiratory pressure(PEEP) of 5 cmH2O during positve&#45

pressure ventilation(PPV). ,Using positive end&#45

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Birth expected at less than 32 completed weeks gestation or estimated birthweight less than 1500 g 2) Mother presenting in sufficient time to receive antenatal counseling and steroids 3) Parental consent to the study

Exclusion criteria

Exclusion criteria: 1) Known congenital abnormality that could affect oxygenation, or surviva or cardiorespiratory function 2) Infants do not require positive-pressure ventilation

Design outcomes

Primary

Measure	Time frame
Peripheral oxygen saturation from 1 to 10 minutes after birth Peripheral oxygen saturation using pulse oximeter	—

Secondary

Measure	Time frame
oxygen requirement from 1 to 10 minutes after birth FiO2	—

Countries

Thailand

Contacts

Public ContactRatchada Kitsommart

Siriraj Hospital, Mahidol University

rkitsommart@hotmail.com024195713

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026