Calcitriol combined with ergocalciferol in CKD with proteinuria

A Double-blind ,randomized,placebo-controlled trial of calcitriol combined with ergocalciferol in CKD with proteinuria

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20140929002

Enrollment

140

Registered

2014-09-29

Start date

2014-07-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Do both natural vitamin D (ergocalciferol) and active viatamin(calcitriol) decrease proteinuria in CKD stage 3 and 4 with proteinuria more than 1 gram/day?

Interventions

in this arm &#44

the patients will receive both Ergocaliferol and calcitriol,in this arm &#44

the patient will receive ergocalciferol and placebo

Active Comparator Drug,Placebo Comparator Drug

recieve Calcitriol combined with ergocalciferol,receive ergocalciferol and placebo

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: the patients are age more than 18 years old and 1. Chronic kidney failure stage 3 -4 2.proteinuria mora than 1 gram per day 3. Serum 25(OH)D (vitamin D level) less than 30 ng/ml

Exclusion criteria

Exclusion criteria: 1.active glomerulonephritis 2.recieve immunosuppressive drug within 3 months 3.adjust dose of ACEI/ARB , Phosphate binder or recieve within 3 months before enrollment 4.serum Calcium more than 10.2 mg/dl

Design outcomes

Primary

Measure	Time frame
proteinuria 12 wk urine protein creatinine ratio	—

Secondary

Measure	Time frame
progression of kidney function 12 wk serum creatinine	—

Countries

Thailand

Contacts

Public Contactsiriwan nakwan

Faculty of Medicine,Chulalongkorn University

porcushow_789@hotmail.com0815716601

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026