Skip to content

Comparison between low dose ketamine VS fentanyl combined with propofol in patients scheduled to have fractional curettage; A randomized controlled trial.

Comparison between low dose ketamine VS fentanyl combined with propofol in patients scheduled to have fractional curettage; A randomized controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20140828001
Enrollment
Unknown
Registered
2014-08-28
Start date
2009-07-13
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine curettage Ketamine&#44

Interventions

Ketamine 0.1 mg/kg was injected intravenously followed by propofol 1.5 mg/kg&#44
then uterine curettage was started along with propofol infusion of 5 mg/kg/hr.,Fentanyl (1 mcg/kg) was injected intravenously&#44
followed by propofol 1.5 mg/kg&#44
then uterine curettage was started along with propofol infusion of 5 mg/kg/hr.
Experimental Drug,Active Comparator Drug
Ketamine,Fentanyl

Sponsors

Faculty of Medicine, Siriraj Hospital, Mahidol University
Lead Sponsor
Department of Anesthesiology&#44
Collaborator
Faculty of Medicine&#44
Collaborator
Siriraj Hospital&#44
Collaborator
Mahidol University
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patient undergoing uterine curettage

Exclusion criteria

Exclusion criteria: BMI more than 30 kg/m2 ASA physical status more than II allergic to propofol, ketamine or fentanyl, psychiatric problem that may get worse by ketamine hypertension that needs medication history of coronary artery disease and increased ICP

Design outcomes

Primary

MeasureTime frame
patient movement During operation Frequency of movement

Secondary

MeasureTime frame
Hypotension During operation Blood pressure,Bradycardia During operation Herat rate,Hypoventilation During operation Respiratory rate,Apnea During operation Ceassation of respiration,Desaturation During operation Pulse oximetry,Recovery time After operation Recovery time,Surgeon satisfaction After operation Score,Postoperative nausea, dizziness and vomitting After operation Number and severity of event

Countries

Thailand

Contacts

Public ContactPoom Tritrakarn

department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University

poompoosup@gmail.com021497990

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026