The patients who were diagnosed as Primary Osteoarthritis of knee with grade I-
Conditions
Interventions
Benjakul recipe capsule at dose of 100 mg three times a day after meal daily for 28 days,diclofenac capsule at dose of 25 mg three times a day after meal daily for 28 days
Experimental Drug,Active Comparator Drug
Benjakul recipe,diclofenac
Sponsors
Thai Traditional Medical Knowledge Fund
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1 Patients with primary osteoarthritis of knee with grade I III of Kellgren Lawrence criteria 2 Not during breast feeding 3 Not during pregnancy with a good contraception 4 Volunteer have a normal Complete Blood Count laboratory lipid profiles liver function tests and renal funtion tests 5 Do not abuse drugs 6 Good cooperation
Exclusion criteria
Exclusion criteria: 1 BMI> 32 2 History of peptic ulcer or Gastroesophageal reflux disease or heart disease liver or disease or kidney disease 3 History of allergy diclofenac drug or allergy herbal medicine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score 1 month Visual analog scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score 1 month Modified WOMAC score (from Modified Thai WOMAC index) | — |
Countries
Thailand
Contacts
Public ContactPiya Pinsornsak
Faculty of Medicine, Thammasart University
Outcome results
None listed