A randomized, controlled trial of early versus late initiation of peritoneal dialysis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20140814001

Enrollment

400

Registered

2014-08-14

Start date

2014-10-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

end stage renal disease patients ESRD Peritoneal dialysis glomerular filtration rate initiation of dialysis

Interventions

initiation of peritoneal dialysis when GFR > 6 ml/min/1.73m2,initiation of peritoneal dialysis when GFR </= 6 ml/min/1.73m2

Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery

early dialysis,late dialysis

Eligibility

Sex/Gender

All

Age

20 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1 CKD stage 5 patients with GFR 9 ml min 1 73m2 2 age 20 years and willing to participate in this study 3 under optimal care by nephrologist at least 2 months before initiation of peritoneal dialysis 4 under NHSO National health security office Thailand coverage

Exclusion criteria

Exclusion criteria: 1 planned living related kidney transplantation 2 cancer disease with expected survival time less than 3 years 3 patients with indication for emergency dialysis including uremia pulmonary edema dyspnea resistant hypertension significant acidemia hyperkalemia unresponse to medical treatment

Design outcomes

Primary

Measure	Time frame
survival rate 3 years after initiation of dialysis survival rate	—

Secondary

Measure	Time frame
1. Disease complications 3 years after initiation of dialysis a. Myocardial infarction b. Cerebrovascular event c. Infection,2. Dialysis complications 2 years after initiation of dialysis a. PD-related Peritonitis, exit site infection/tunnel infection b. Non-infectious complication c. Em,3. Quality of life every 6 months assess by EQ-5D-5L,4. Hospitalization every 6 months time to first hospitalization, total admission day,5. Residual renal function every 6 months rate of decline,6. Technique survival every 6 months dialysis mode,7. Nutritional assessment every 6 months malnutrition inflammation score,8. Economic evaluation every 6 months direct and indirect cost	—

Measure

Time frame

1. Disease complications 3 years after initiation of dialysis a. Myocardial infarction b. Cerebrovascular event c. Infection,2. Dialysis complications 2 years after initiation of dialysis a. PD-related Peritonitis, exit site infection/tunnel infection b. Non-infectious complication c. Em,3. Quality of life every 6 months assess by EQ-5D-5L,4. Hospitalization every 6 months time to first hospitalization, total admission day,5. Residual renal function every 6 months rate of decline,6. Technique survival every 6 months dialysis mode,7. Nutritional assessment every 6 months malnutrition inflammation score,8. Economic evaluation every 6 months direct and indirect cost

—

Countries

Thailand

Contacts

Public Contactsomchai yongsiri

Burapha University

syongsiri@yahoo.com66-81-0011018

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

A randomized&#44; controlled trial of early versus late initiation of peritoneal dialysis