total propofol dose stable hemodynamic time to Aldrete score 9 serious adverse event EGD-
Conditions
Interventions
Bolus dose of fentanyl 1 ug/ml at the beginning of the procedure before start propofol-
based sedation 1 min.,Bolus dose of ketamine 0.3 mg/kg at the beginning of the procedure at the beginning of the procedure before start propofol-
based sedation 1 min.
Active Comparator Drug,Experimental Drug
fentanyl,ketamine
Sponsors
Golden Jublee Medical Center, Mahidol University
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: Patients will be enrolled if they were 65 90 years old who underwent elective EGD colonoscopy under intravenous sedation with Propofol based Patients who were ASA I -III
Exclusion criteria
Exclusion criteria: Had history of severe cardiac disease ejection fraction 30 allergy to anesthetics Had history of neurologic disease seizure glaucoma Had history of chronic opioid used or sedative drugs morbid obesity BMI 35 poorly control hypertension severe hypertension SBP 160 mmHg Had history of psychiatric disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| total propofol dose at end of procedure Total dose of propofol (mg) | — |
Secondary
| Measure | Time frame |
|---|---|
| time to aldrete score 9 at time that patient had aldrete score 9 in recovery room minute since end of operation to patient had aldrete score 9,hemodynamic response between group baseline, after induction, then every 5 minute until 60 minute BP, RR, SpO2 | — |
Contacts
Public ContactMutita Kunopart
Mahidol Unversity
Outcome results
None listed