The bone defect healing after periapical surgery Acemannan Bone healing Radiographic Periapical surgery Phase 2 clinical trial
Conditions
Interventions
10 mg acemannan sponges will be inserted into bone defect,0.5cc DBM putty (DBX,
USA) is used in each bone defect.
Experimental Other,Active Comparator Other
Acemannan sponges,Demineralized bone matrix
Sponsors
National Research Council of Thailand
Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Patient presents a radiolucency periapical lesion with 5 to 15 mm diameter size of anterior teeth Abnormalities of dental pulp and root shape Restoration considerations such as crown or post in the root canals Horizontal fractures Breakage instruments or extrument of filling materials Referance from endodontist to do periapical surgery
Exclusion criteria
Exclusion criteria: Allergy to anesthetics or herbal medicines pregnant women Smoker addition Alcohol drinkers Enable teeth for root canal retreatment Compromise of crown root ratio Lesions close to the mental forament or nasal cavities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone healing 3 and 6 months postoperation Radiographic density | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical signs 1 and 7 days Pain scale, swelling scale | — |
Countries
Vietnam
Contacts
Public ContactVan Le
40A, Trang Thi street, Hoan Kiem district, Hanoi, Vietnam
Outcome results
None listed