THE EFFECT OF ACEMANNAN SPONGE ON TOOTH SOCKET HEALING

Acemannan induces bone formation in tooth socket: clinical and radiographic evaluation

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20140701001

Enrollment

Registered

2014-07-01

Start date

2015-01-12

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The socket healing after tooth extraction Acemannan Bone healing Tooth socket Radiography Morbidity Phase 2 clinical trial

Interventions

50mg acemannan sponge is inserted into each sockets and is expected to induce bone formation in tooth sockets after extraction,0.5cc DBM putty (DBX&#44

Synthes&#44

USA) is used in each socket.

Experimental Other,Active Comparator Other

ACEMANNAN SPONGE,DEMINERALIZED BONE MATRIX (DBM)

Eligibility

Sex/Gender

All

Age

18 Years to 25 Years

Inclusion criteria

Inclusion criteria: Healthy non systemic disorder patients Mesioangular or vertical impacted lower third molar

Exclusion criteria

Exclusion criteria: Pregnant women Alcohol drinkers Smokers Patients with systemic diseases pathological condition or local oral infection Allergic to aloe vera gel or collagen

Design outcomes

Primary

Measure	Time frame
Bone formation 3 and 6 month after experiment Radiographic Density	—

Secondary

Measure	Time frame
Morbidity after extraction 24 and 48 hours after operation Pain scale and swelling scale	—

Countries

Vietnam

Contacts

Public ContactTien Tien

Hanoi National Hospital of Odonto - Stomatology

vu.thuytien86@gmail.com+84985792886

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026