the efficacy of plasmin-
Conditions
Interventions
plasmin enzyme assisted vitrectomy
Active Comparator Drug
plasmin enzyme
Sponsors
Chang Gung Medical Research Project (CMRPG381661)
Chang Gung Medical Research Project (CMRPG381661)
Eligibility
Sex/Gender
All
Age
0 Months to 16 Years
Inclusion criteria
Inclusion criteria: Patients aged 16 years or younger with vitreoretinopathy associated with abnormal vitreoretinal adhesion were enrolled for the use of plasmin as an adjuvant to vitreoretinal surgery
Exclusion criteria
Exclusion criteria: Patients with active human immunodeficiency virus hepatitis B virus or hepatitis C were excluded from this trial Eyes with PVD at presentation sign of active infection history of uveitis or glaucoma uncontrolled by ocular hypotensive agents were excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the induction of posterior vitreous detachment during the surgery intraoperative period and postoperative 1 day,1 week, 2 weeks, 1 month, 2 months, 3 months, 6 months percentage of posterior vitreous detachment during surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| the restoration of retinal anatomy and visual acuity postoperative 1 day, 1 week, 2 weeks, 1 month, 2 months, 3 months, 6 months visual acuity (logMAR unit); fundus photography, optical coherence tomography | — |
Countries
Taiwan
Contacts
Public ContactWu Wei-Chi
Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan
Outcome results
None listed