Efficacy of paracetamol and chlorpheniramine maleate premedication for preventing blood transfusion reactions in pediatric thalassemic patients

comparison paracetamol and CPM for transfusion reaction in thallasemic pediatric patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20140526001

Enrollment

140

Registered

2014-05-26

Start date

2014-06-05

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

transfusion reaction transfusion reaction

Interventions

combine paracetamol and chlorphenniramine maleate,normall saline

Active Comparator Drug,Placebo Comparator Drug

paracetamol and chlorphenniramine maleate,placebo

Eligibility

Sex/Gender

All

Age

6 Months to 25 Years

Inclusion criteria

Inclusion criteria: 1 thallasemic patients 2 receive red cell transfusion

Exclusion criteria

Exclusion criteria: 1 history of transfusion reaction 2 history of dgruallergy to paracetamo and cpm 3 dedied to enrolled in study

Design outcomes

Primary

Measure	Time frame
fever 24 hrs randomised double-blinded controlled,fever 24 hrs randomised double-blinded controlled	—

Secondary

Measure	Time frame
urticaria 24 hrs randomised double-blinded controlled,urticaria 24 hrs randomised double-blinded controlled	—

Countries

Thailand

Contacts

Public Contactchanchai traivaree

phramongkutklao college of medicine

ctrivaree@yahoo.com0817556677

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026