First trimester termination of pregnancy The effectiveness of Misoprostol for cervical preparation before manual vacuum aspiration first trimester abortion misoprostol cervical dilatation manual vacuum aspiration
Conditions
Interventions
Sublingual group (SG) received a 400 µ
g misoprostol sublingually plus on an oral placebo two hours prior to manual vacuum aspiration.,Oral group (OG) received a 400 µ
g misoprostol orally and a sublingual placebo two hours prior manual vacuum aspiration.
Active Comparator Drug,Active Comparator Drug
sublingual misoprostol,oral misoprostol
Sponsors
Faculty of medicine, Thammasat University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: A singleton intrauterine pregnancy equal or less than 12 weeks gestational age with a diagnosis of early pregnancy failure blighted ovum anembryonic gestation and embryonic death no cardiac activity visible on TVS when the embryo measures 5 mm or more in length The gestational age was verified by a reliable menstrual history and confirmed by physical or ultrasound examination
Exclusion criteria
Exclusion criteria: A history of misoprostol allergy anticoagulant usage clinical coagulopathy bleeding disorder hypertension chronic illness active pelvic inflammatory disease inevitable and incomplete abortion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cervical dilatation was measured prior to Manual Vacuum Aspiration The cervical width was measured prior to Manual Vacuum Aspiration cervical width was measured by largest Hegar’s dilators that pass through cervix without resistance | — |
Secondary
| Measure | Time frame |
|---|---|
| pain scores and patient satisfactions after finished manual vacuum aspiration visual analogue 10cm-scale with zero to 10 | — |
Countries
Thailand
Contacts
Public ContactDensak pongrojpaw
Department of Obstetrics and Gynaecology, Faculty of medicine, Thammasat University
Outcome results
None listed