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A Randomized Controlled Trial of Sustained Lung Inflation for Resuscitation of Preterm Infants in Delivery Room

A Randomized Controlled Trial of Sustained Lung Inflation for Resuscitation of Preterm Infants in Delivery Room

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20140418001
Enrollment
80
Registered
2014-04-18
Start date
2014-04-02
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Born at 25 to 32 weeks� gestation Requires a positive pressure ventilation or CPAP in delivery room Preterm Resuscitation

Interventions

After oropharyngeal and nasal suctioning&#44
infants in the SLI group will undergo the following approaches&#44
controlled (25 cmH2O) inflation will be sustained for 15 seconds&#44
using an appropriate size&#44
neonatal mask and T&#45
piece resuscitator followed by the delivery of 6 cmH2O NCPAP. Infants will be observed for the following 6 to 10 seconds to evaluate their cardio&#45
respiratory function.,infant in control group will be resuscitated according to the current AAP Guidelines
sustained lung inflation,Control

Sponsors

Ramathibodi Research Fund
Lead Sponsor
Ramathibodi Research Fund
Collaborator

Eligibility

Sex/Gender
All
Age
1 Years to 10 Years

Inclusion criteria

Inclusion criteria: 1 Born at 25 to 32 weeks gestation and 2 Those requires a positive pressure ventilation or CPAP in delivery room

Exclusion criteria

Exclusion criteria: 1 Presence of major congenital malformations 2 Hydrops fetalis 3 Prenatal diagnosis of upper airway obstruction 4 Meconium stained amniotic fluid

Design outcomes

Primary

MeasureTime frame
Intubation in delivery room In delivery room Intubation rate

Secondary

MeasureTime frame
bronchopulmonary dysplasia (BPD) At 36 wk PMA BPD rate

Countries

Thailand

Contacts

Public ContactPracha Nuntnarumit

Ramathibodi Hospital

pracha.nun@mahidol.ac.th0819475906

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026