efficacy of nortriptyline in functional dyspepsia

Efficacy of Nortriptyline in Functional dyspepsia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20140327001

Enrollment

Registered

2014-03-27

Start date

2012-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional dyspepsia dyspepsia nortriptyline antidepressant

Interventions

Nortriptyline 10 mg giving hs in white capsule,Same white capsule giving 1 capsule hs

Experimental Drug,Placebo Comparator Drug

Nortriptyline,Placebo

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: patients age 18 60 year diagnosed of functional dyspepsia symptoms fail to response 2 month course of PPI or prokinetics therapy

Exclusion criteria

Exclusion criteria: patients with psychological problems or severe medical comorbid disease patients who currently taking antidepressant anxiolytics patients with history of nortriptyline allergy

Design outcomes

Primary

Measure	Time frame
Response rate percent	—

Secondary

Measure	Time frame
Side effect percent	—

Countries

Thailand

Contacts

Public ContactUayporn Kaosombatwattana

uayporn.kao@mahidol.ac.th6624197281

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026