Chronic rhinosinusitis patients saline nasal irrigation,
Conditions
Interventions
irrigate nasal cavity through nostrils by using 250ml of 38-
40 degree Celsius Normal saline ,irrigate nasal cavity through nostrils by using 250ml of 21-
24 degree Celsius Normal saline
Experimental Drug,Active Comparator Drug
Warm saline nasal irrigation,room temperature nasal irrigation
Sponsors
Department of Otorhinolaryngology, Faculty of Medicine, Chulalongkorn University
Department of Otorhinolaryngology,
Faculty of Medicine,
Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Chronic rhinosinusitis patients fulfill EPOS2012 criterias Has moderate or severe severity (by visual analog scale more than 5) No recent sinusitis treatment within 1 month
Exclusion criteria
Exclusion criteria: Has been diagnosed with congenital mucociliary or mucosal diseases e.g. Primary ciliary dyskinesia, cystic fibrosis has been diagnosed with immuno-deficiency disease e.g. diabetes mellitus, AIDS Large nasal polyp (grade 3) Fungal rhinosinusitis or fungal ball has been diagnosed with systemic vasculitis or granulomatous disease History of Cocaine abuse Has been diagnosed with tumor in nasal cavity or paranasal sunus Has severe nasal septum deviation that may interfere nasal irrigation Recent medication that may alter muciliary function e.g. 1st generation antihistamine within 3 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mucociliary clearance 1 hour Saccharine transit time | — |
Secondary
| Measure | Time frame |
|---|---|
| Symptom score 1 hour obstructive symptom score,Comfortability 1 hour comfortability symptom score,Objective score 1 hour peak nasal inspiratory flow,Objective score 1 hour rhinomanometry,Objective score 1 hour acoustic rhinometry | — |
Countries
Thailand
Contacts
Public ContactSaran Ruxrungtham
Department of Otorhinolaryngology, Faculty of Medicine, Chulalongkorn University
Outcome results
None listed