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EFFICACY AND SAFETY OF GINGER EXTRACT NANOPARTICLES RELIEVES PAINS IN KNEE OSTEOARTHRITIS

FFICACY AND SAFETY OF GINGER EXTRACT NANOPARTICLES RELIEVES PAINS IN KNEE OSTEOARTHRITIS

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20140306001
Enrollment
120
Registered
2014-03-06
Start date
2014-04-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee pain Knee osteoarthritis WOMAC KOOS

Interventions

The ginger extract NLC is base on an extract of the Zingiber officinale rhizome which is extracted by acetone. The ginger extract’s preparation is conducted to form a Nanostructure Lipid Carrier.Takin
Experimental Drug,Active Comparator Drug
ginger extract with NLC,1% Diclofenac gel

Sponsors

Chulalongkorn University
Lead Sponsor
Thai Traditional knoleage fund
Collaborator

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Both male and female age > 50 yrs. 2.Primary OA knee 3.The severity of OA knee on ISOA index mild or moderate 4.Patients grade II-III of Kellgren and Lawrence criteria 5.Good communication and cooperation

Exclusion criteria

Exclusion criteria: 1.History of allergy herbs used medicinally during investigation 2.History of cancer, diabetes, paralysis and unknown infection disease

Design outcomes

Primary

MeasureTime frame
Knee pain 3 months WOMAC Score , KOOS score,Pain score 3 months Visual analog scale

Secondary

MeasureTime frame
Quality of life 3 month KOOS score

Contacts

Public ContactSurasak Taneepanichskul

College of Public Health Sciences

surasak@chula.or.th0899864839

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026