catheter-
Conditions
Interventions
tramadol 1.5 mg/kg diluted with normal saline solution into 5 ml intravenous before urinary catheterization,ketamine 0.5 mg/kg diluted with normal saline solution into 5 ml intravenous before urinary
tramadol,ketamine,placebo
Sponsors
Chulalongkorn University
Department of Anesthesiology,
Faculty of Medicine,
Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: adult patients aged 18-70 years old with American Society of Anesthesiologists physical status I and II undergoing elective laparoscopic surgery at King Chulalongkorn Memorial Hospital
Exclusion criteria
Exclusion criteria: patients requiring postoperative ICU admission and respiratory support history of chronic pain or chronic analgesic usage or chemical substance abuse history of overactive bladder (OAB) defined as urination frequency more than 3 times at night or 8 times during a 24-hour period history of bladder outlet obstruction or benign prostatic hypertrophy disturbance of the central nervous system severe cardivascular or hepatic disease end stage renal disease (urine output less than 500 ml/24 hour morbid obesity (BMI >=35) hypersensitivity to tramadol or ketamine patients who are unable to communicate patients with difficulty in urinary catheterization duration of surgery longer than 4 hours conversion to laparotomy pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Catheter related bladder discomfort at 0, 1, 2, 6 and 24 hour after admitting to post-anesthetic care unit visual analogue scale | — |
Secondary
| Measure | Time frame |
|---|---|
| side effects of study drugs at 0, 1, 2, 6 and 24 hour after admitting to post-anesthetic care unit 4 point rating scale,post-operative pain score at 0, 1, 2, 6 and 24 hour after admitting to post-anesthetic care unit visual analogue scale | — |
Countries
Thailand
Contacts
Public ContactRattanaporn Burimsittichai
Department of Anesthesiology, Faculty of Medicine, Chulalongkorn University
Outcome results
None listed