Patients with gallstone who underwent laparoscopic cholecystectomy Etoricoxib Low pressure Standard pressure Pneumoperitoneum Laparoscopic cholecystectomy
Conditions
Interventions
Intervention Classification is the combination of drug and surgical procedure,Intervention Classification is the combination of drug and surgical procedure
1) Oral preemptive analgesia (etoricoxib 120 mg) 2) Intraabdominal pressure 7 mmHg,1) Oral placebo 2) Intraabdominal pressure 14 mmHg
Sponsors
Royal College of Surgeons of Thailand
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: ASA 1-2 patients age 18-75 years requiring elective laparoscopic cholecystectomy were eligible for enrollment in the study.
Exclusion criteria
Exclusion criteria: 1) Acute preoperative pain other than biliary colic 2) Require chronic pain treatment 3) Advanced renal disease (creatinine clearance 35 kg/m2) 9) Contraindication for etoricoxib such as ischemic heart disease, severe hepatic impairment (Child-Pugh score > 9), lactating patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score at rest and on movement At 1, 2 hours postoperatively, and then every 4 hours until discharge Numeric rating scale (0-10) | — |
Secondary
| Measure | Time frame |
|---|---|
| analgesic drug use At 1, 2 hours postoperatively, and then every 4 hours until discharge Record rescuse drug | — |
Contacts
Public ContactWasana Ko-iam
Chiang Mai University
Outcome results
None listed