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Risk Factors and Chemoprophylaxis for Leptospirosis Infection during Urban Flooding in Southern Thailand: A Case-Control Study

Risk Factors and Chemoprophylaxis for Leptospirosis Infection during Urban Flooding in Southern Thailand: A Case-Control Study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20131106001
Enrollment
1000
Registered
2013-11-06
Start date
2010-10-08
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Leptospirosis infection after flooding Symptomatic leptospirosis infection after flooding Leptospirosis infection Symptomatic leptospirosis infection

Interventions

Two tablets of 100&#45
mg doxycycline were given to compliant participants without a history of tetracycline or doxycycline allergy. The participants were observed 2 hours after taking doxycycline.
Active Comparator Drug
Doxycycline 200 mg for prophylaxis leptospirosis after flooding

Sponsors

Faculty of Medicine, Prince of Songkla University
Lead Sponsor
Faculty of Medicine&#44
Collaborator
Prince of Songkla University
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: All residents who lived in the municipality area of Hat Yai city, aged 18 years or above and were exposed to flood water since October 3 were eligible to be enrolled in this study.

Exclusion criteria

Exclusion criteria: Pregnant women, lactating mothers and those who felt sick with any disease or took any antibiotics before the enrollment period were excluded.

Design outcomes

Primary

MeasureTime frame
Leptospirosis infection 3 weeks after recruitment number of patients

Secondary

MeasureTime frame
Symptomatic leptospirosis INfection 3 weeks after recruitment number of patients

Countries

Thailand

Contacts

Public ContactSarunyou Chusri

Division of Infectious Disease, Department of Internal Medicine, Faculty of Medicine, Prince of Song

sarunyouchusri@hotmail.comUSA 4126324984

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026