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Low pressure support vs T-piece method for discontinuation from mechanical ventilator

Low pressure support vs T-piece method for discontinuation from mechanical ventilator

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20130921001
Enrollment
520
Registered
2013-09-21
Start date
2011-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilatory associated pneumonia (VAP), Length of Sub-ICU and ICU stay, Re-intubation rate in 48 hrs, Length of hospital stay Ventilatory associated pneumonia (VAP), Length of Sub-ICU and ICU stay, Re-intubation rate in 48 hrs, Length of hospital stay

Interventions

weaning off ventilator by pressure support mode (PS) of ventilator with Pressure support 5 cmH2O at least 2 hour ,weaning off ventilator by T&#45
piece method with oxygen supplement 10 LPM at least 2 hour
Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery
Group A,Group B

Sponsors

Faculty of Medicine CMU
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 100 Years

Inclusion criteria

Inclusion criteria: Causes of ventilatory use can corrected , Effector cough to expectorant secretion. Hemodynamically stable SBP is more than 90 and less than 180 mmHg. Heart rate less than 120 beat per minute , PaO2/FiO2 more than 200, PEEP less than or equal 5-8 cmH2O, RR/spontanepus Vt (Rapid shallow breathing) less than 100 breaths per minute, FiO2 less than 0.4-0.5 LPM; No relaxant use, pH greater than 7.25, VE 5 to 15 L/min, Tidal volume more than 4 ml/kg, Hemoglobin more than 8 g/dl Pain score less than 5, Ready to wean, 3 minute success, and Spontaneous breathing trial (SBT) success

Exclusion criteria

Exclusion criteria: Uncorrectable causes of respiratory failure, such as irreversible respiratory muscle peralysis or central nervous system defect, Heart failure, Chronic obstructive pulmonary disease

Design outcomes

Primary

MeasureTime frame
Ventilatory associated pneumonia (VAP) 2013 Prospective,Re-intubation rate in 48 hrs 2013 Prospective,Length of Ventilatory used 2013 Prospective

Secondary

MeasureTime frame
Length of Sub-ICU and ICU stay 2013 Prospective,Length of hospital stay 2013 Prospective

Countries

Thailand

Contacts

Public ContactKaweesak Chittawatanarat

Chiang Mai University

kchittaw@gmail.com66815951259

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026