Atherosclerotic patients. Atherosclerotic risk patients. Atherosclerosis Atherosclerotic Coronary artery disease Cerebrovascular disease Peripheral arterial disease Risk factor
Conditions
Interventions
patients with high risk for cardiovascular events.
Prevention
High risk for cardiovascular events group
Sponsors
The Heart Association of Thailand under the Royal Patronage of H.M.
National Research Council of Thailand
Eligibility
Sex/Gender
All
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients who are age at least 45 year old with either high atherosclerotic risk (group 1) or established atherosclerotic cv disease (group 2) Group 1: Patients with The CORE Thailand is conducting to study the risk factors of atherosclerotic risk patients and patients with established atherosclerotic disease (coronary artery disease, cerebrovascular disease and peripheral arterial disease), the cardiovascular event rate in these population, the treatment and investigation for atherosclerotic disease greater than or equal to 3 risk factors as following: 1.1 Diabetes (type 1 or 2) or impaired fasting glucose 1.2 Hypertension (BP less than140/90 mmHg or currently treated with antihypertensive agent) 1.3 Chronic kidney disease stage I-IV 1.4 Dyslipidemia 1.5 Smoking 1.6 Male greater than or equal to 55 year old and woman greater than or equal to 65 year old 1.7 family history of premature atherosclerosis Group 2. Patients with established atherosclerotic disease 2.1 Patients with cerebrovascular disease: transient ischemic attack, ischemic stroke 2.2 Patients with coronary artery disease: stable angina with evidence of myocardial ischemia, acute coronary syndrome, underwent coronary angioplasty/stenting or coronary artery bypass graft, coronary stenosis more than 50 percent by coronary angiogram or coronary CT angiogram 2.3 patients with peripheral arterial disease: intermittent claudication with Ankle Brachial Index less than 0.9, intermittent claudication with history of intervention (angioplasty, Vascular bypass graft or amputation)
Exclusion criteria
Exclusion criteria: 1. Patients with recent episodes of acute cariovascular event (within 3 months) 2. Patients who are currently in blinded study 3. Patients with life expectancy less than 3 years from other illness such as AIDS or cancer 4. Patients with surgically indicated aortic aneurysm 5. Patients with difficulty of follow up 6.Patients who do not give consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major adverse cardiovascular events 6,12,24,36,48,60 months event rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Risk factors of cardiovascular events 6,12,24,36,48,60 months Risk factors, Cardiovascular events | — |
Countries
Thailand
Contacts
Public ContactArintaya Phrommintikul
Faculty of Medicine, Chiang Mai University
Outcome results
None listed