intraocular pressure primary angle closure glaucoma primary open angle glaucoma intraocular pressure 24 hour IOP fluctuation primary angle closure glaucoma primary open angle glaucoma Icare tonometer
Conditions
Interventions
None listed
Sponsors
Quality improvement fund, King Chulalongkorn Memorial Hospital
King Chulalongkorn Memorial Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 90 Years
Inclusion criteria
Inclusion criteria: ≥ 40 years old, spherical refractive error < 6 diopters, astigmatism < 3 diopters, no history of intraocular surgery except uncomplicated phacoemulsification with intraocular lens, no previous ocular trauma, corneal, retinal or ocular inflammatory diseases, and no systemic disease that could interfere with 24-hour IOP measurement. All patients had to have glaucomatous optic neuropathy with characteristic visual field defect. A glaucomatous optic neuropathy was a vertical cup to disc ratio of more than 0.7 or focal neuroretinal rim loss in the superior or inferior quadrant. An automated standard perimetry was performed using Swedish Interactive Threshold Algorithm (SITA) standard 24-2 (Carl Zeiss Meditec, Dublin, CA, USA). A characteristic visual field defect was defined as a reliable visual field with less than 30% fixation loss, false positive and false negative errors showed an outside normal limits on glaucoma hemi-field test or pattern standard deviation < 5% on at least two consecutive tests. In the PACG group, the angle had to be closed (no view of the posterior trabecular meshwork) for a minimum of 180 degrees by gonioscopy, and initial IOP was more than 21 mmHg. All PACG patients underwent peripheral iridotomy at least 3 month before included in the study. All of them were treated with topical steroid to control inflammation for 1 week. Patients who had open angle on gonioscope were classified into POAG group. Data was collected from one eye of each patient; if both eyes met the criteria, the eye with more advanced glaucomatous optic neuropathy was included.
Exclusion criteria
Exclusion criteria: Cannot complete 24-hour IOP measurement Previous intraocular surgery Except phacoemulsification with IOL at least 3 months History of intraocular trauma Refractive error Sphere ≥ 6 diopters Astigmatism ≥ 3 diopters
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pattern 24 hour IOP 8 times in 1 day Icare tonometer | — |
Secondary
| Measure | Time frame |
|---|---|
| compare office hours IOP and out of office hours IOP office hours(9am, 12 pm, 3 pm) and out of office hours(6pm, 9pm, 0 am, 3 am, 6am) in 1 day Icare tonometer | — |
Countries
Thailand
Contacts
Public ContactAnita Manassakorn
King Chulalongkorn Memorial Hospital
Outcome results
None listed