Skip to content

What is the effect of isoflurane compared to desflurane on recovery time and post operative nausea in patients undergoing laparoscopic cholecystectomy?

Impact of Isoflurane and Desflurane on Recovery Time and Postoperative Nausea in Patients Undergoing Laparoscopic Cholecystectomy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
SLCTR
Registry ID
SLCTR/2025/039
Enrollment
Unknown
Registered
2025-10-02
Start date
2025-10-06
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting, Laparascopic cholecystectomy

Interventions

Study setting: Combined Military Hospital Multan Method of randomization into study arms: Simple randomization Unit of randomization: Individual Patient Method of sequence generation: Computer-gene

Sponsors

Inshal Jawed
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age >18 years. 2. Males and females 3. Undergoing planned laparoscopic cholecystectomy. 4. ASA (American Society of Anesthesiologists) status I or II. ASA-I : completely healthy individual with no history of smoking or no prior alcohol use. ASA-II: patient with a mild systemic disease but without a major functional limitation (severe renal or hepatic dysfunction).

Exclusion criteria

Exclusion criteria: 1. BMI >35 kg/m² 2. Chronic use of antiemetic 3. Diagnosed severe hepatic or renal dysfunction 4. History of hypersensitivity to inhalational anesthetics

Design outcomes

Primary

MeasureTime frame
Postoperative recovery time The Modified Aldrete Scoring system will be used. A score of ?9 will be used as a reference to discharge the patient from the Post-anesthesia Care Unit, and the time from discontinuation of anesthetic agent to discharge will be measured [Till time of discharge] Incidence of postoperative nausea and vomiting within the first 24 hours postoperatively. [ Incidence of the episode of vomiting and nausea will be recorded during the early (0-6 hours) and late phase (6-24 hours).]

Secondary

MeasureTime frame
None []

Countries

Pakistan

Contacts

Public ContactInshal Jawed

General Physician

inshaljwd@gmail.com

Outcome results

None listed

Source: SLCTR (via WHO ICTRP) · Data processed: Aug 10, 2026