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Comparison of The Open Kinetic Chain and Closed Kinetic Chain Exercises on Physical Function, Balance and Quality of Life of Patients with Moderate Knee Osteoarthritis: A Randomized Controlled Trial

Comparison of The Open Kinetic Chain and Closed Kinetic Chain Exercises on Physical Function, Balance and Quality of Life of Patients with Moderate Knee Osteoarthritis: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
SLCTR
Registry ID
SLCTR/2025/006
Enrollment
Unknown
Registered
2025-02-14
Start date
2025-02-20
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

1. Study area / setting The department of physiotherapy, Teaching hospital, Anuradhapura. 2. Randomization - Patients will be randomized into two groups (close-chain and open-chain exercises groups
repeating the exercise 10 times STATIC BIKE CYCLING EXERCISE (without resistance) KNEE EXTENSION EXERCISE - Participants in a high sitting position a towel roll will be used for protection of the popl

Sponsors

Department of Physiotherapy, Teaching Hospital, Anuradhapura, Sri Lanka
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Medical conditions - Male and female patients who are medically diagnosed with moderate bilateral osteoarthritis attending to the department of physiotherapy, Teaching hospital, Anuradhapura. Moderate bilateral osteoarthritis will be diagnosed using Kellgren-Lawrence Scale – grade 3, by the consultant rheumatologist of Teaching Hospital Anuradhapura Age - Above 40 years of age.

Exclusion criteria

Exclusion criteria: 1. Patients with comorbid neurological conditions - Alzheimer's disease, Amyotrophic lateral sclerosis (ALS) or Lou Gehrig's disease, Brain cancer, Cerebral palsy, Epilepsy, Multiple sclerosis (MS), Parkinson's disease, Stroke,Traumatic brain injury. 2. Patients with severe systemic diseases - refer to conditions affecting the entire body, rather than a single organ or body part. Diabetes, Gout, Lupus, Scleroderma,Dermatomyositis, Malaria,, Lymphogranuloma venereum (LGV) , Chronic fatigue syndrome, Heart disease, Stroke, HIV, Asthma, Crohn's disease, and Muscular dystrophy. 3. Patients who cannot walk independently 4. Patients who have undergone knee/hip or ankle surgeries. 5. Patients with congenital abnormalities. 6. Patients who cannot provide with informed written consent.

Design outcomes

Primary

MeasureTime frame
Anthropometry [Baseline, 1st 4 weeks and at the end of 8th week] The Knee Injury and Osteoarthritis Outcome Score (KOOS) (QOL-quality of life will be assessed using the KOOS questionnaire, which is included as a sub section of the questionnaire [ Baseline, 1st 4 weeks and at the end of 8th week] Burge Balance Scale [ Baseline, 1st 4 weeks and at the end of 8th week] The Knee Injury and Osteoarthritis Outcome Score (KOOS) (QOL-quality of life will be assessed using the KOOS questionnaire, which is included as a sub section of the questionnaire [ Baseline, 1st 4 weeks and at the end of 8th week] Burge Balance Scale [ Baseline, 1st 4 weeks and at the end of 8th week]

Secondary

MeasureTime frame
None []

Countries

Sri Lanka

Contacts

Public ContactDMAK Dissanayake

Physiotherapist

asirinidissanayake93@gmail.com0252222261

Outcome results

None listed

Source: SLCTR (via WHO ICTRP) · Data processed: Aug 10, 2026