A single arm non randomized study on the effects of phone aided cognitive rehabilitation (PACR) on cognition in patients with cognitive decline due to hippocampal sclerosis (HS) and temporal lobe epilepsy (TLE) at the National Hospital of Sri Lanka

Assessment of prevalence and pattern of cognitive dysfunction in patients with hippocampal sclerosis (HS) and temporal lobe epilepsy (TLE) and the effects of phone aided cognitive rehabilitation (PACR) on patients with cognitive decline due to TLE and HS in a Tertiary Care Hospital in Colombo, Sri Lanka

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

SLCTR

Registry ID

SLCTR/2022/019

Enrollment

243

Registered

2022-08-08

Start date

2022-08-08

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporal lobe epilepsy

Interventions

Study setting: National Hospital of Sri Lanka Method of randomization: none, this is a single arm uncontrolled study. Intervention: This is a phone aided cognitive rehabilitation (PACR) programme and

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients (males and females) with a confirmed diagnosis of TLE and HS aged 18 – 60 years with cognitive impairment detected at baseline of the study 2. Subjects who have access to a smart phone of any kind and can operate the phone.

Exclusion criteria

Exclusion criteria: 1. Patients with active psychotic and mood symptoms assessed through the Short General Health Questionnaire (GHQ-12) 2. Patients having delirium/ acute confusion resulting from a recent acute event including seizures. 3. IQ below 70. This will be assessed using Test of Nonverbal Intelligence (TONI-3) study instrument. 4. Patients with an existing diagnosis of learning disability 5. Patients with established cognitive impairment due to other causes than TLE 6. Patients with hearing and visual impairment compromising the ability to coorporate with the tests and the intervention 7. Presence of another neurological disorder (e.g. dementia, stroke, epilepsy, and traumatic brain injury resulting in a loss of consciousness for more than 30 minutes) 8. Patients with a history of photosensitive seizures 9. Patients who are undergoing/have similar intervention/s currently or in the recent past 10. Patients who are undergoing treatment changes or have planned changes to the treatment in the next six months 11. Patients who develop lack of capacity to continue during the study period.

Design outcomes

Primary

Measure	Time frame
Change in mean scores of cognitive functions assessed using Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) scale. RBANS assesses five domains: immediate and delayed memory, attention, visuospatial construction, and language. [[Baseline, 4 weeks, 8 weeks, 12 weeks and at 6 months from initiating the intervention] ]	—

Secondary

Measure	Time frame
1. Improvement in quality of life: This will be assessed using WHOQOL-BREF instrument. 2. Intelligence: This will be assessed using Test of Nonverbal Intelligence (TONI-3) study instrument 3. Psychological status: This will be assessed using General Health Questionnaire-12 (GHQ-12) [[ Baseline, 4 weeks, 8 weeks, 12 weeks and at 6 months from initiating the intervention] ]	—

Countries

Sri Lanka

Contacts

Public ContactDr Kishara Gooneratne

Senior Lecturer

kishig@gmail.com+94773662903

Outcome results

None listed

Source: SLCTR (via WHO ICTRP) · Data processed: Aug 9, 2026