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Pilot study to assess the safety of a newly designed external fixator (MK03) among patients who present with compound fractures of the tibia

Pilot Study to assess safety of new Low Cost External Fixators for Long bone fractures

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
SLCTR
Registry ID
SLCTR/2021/025
Enrollment
30
Registered
2021-09-06
Start date
2021-09-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Compound fractures of tibia

Interventions

1. Study site- Orthopedic wards of the North Colombo Teaching Hospital and National Hospital of Sri Lanka 2. Intervention- The MK03 external fixator will be the new device used. When a patient is admi

Sponsors

Imperial College London
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 years and above 2. Patients who present with compound fractures of the tibia

Exclusion criteria

Exclusion criteria: 1. Patients who present more than 1 week after injury 2. Patients whose fracture pattern requires a joint spanning external fixation 3. Patients who are unable to consent 4. Patients who are immunocompromised or with conditions which delay wound healing.(E.g malignancy, liver, renal disease, on steroids etc)

Design outcomes

Primary

MeasureTime frame
Pin site infection will be graded based on the severity scale for pin site infection – Checketts-Otterburn classification [2,4,6,8 and 12 weeks] Pin loosening – This is a clinical assessment which has a binary, ‘Yes’ or ‘No’ value [ 2,4,6,8 and 12 weeks] Stability of the construct - This is a clinical assessment which has a binary, ‘Yes’ or ‘No’ value [ 2,4,6,8 and 12 weeks] Progression of soft tissue healing – Based on the final treatment – a. Primary closure achieved b. Delayed primary closure achieved c. Closure with skin graft d. Local tissue transfer e. Free tissue transfer f. Amputation [ 2,4,6,8 and 12 weeks] [] [] [] [] [ ] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [] []

Secondary

MeasureTime frame
Evidence of deformed clamp sites:Visual inspection using pre and post images. The image will be taken in the Orthogonal view to the clamp axis for this purpose. Binary scale (“Yes”/”No”) will be used to measure the outcome [2,4,6,8 and 12 weeks] Evidence of damage to any fixator, measured by visual inspection using pre and post images. The image will be taken in the Orthogonal view to the clamp axis for this purpose. Binary scale (“Yes”/”No”) will be used to measure the outcome [ 2,4,6,8 and 12 weeks] Extent of fixator slippage between interfaces:Measured by orthogonal x rays taken immediately post op and during follow up will be used. By comparing orthogonal x ray, with the previous x ray, any change in position of the screws, clamps and rods, in axial, sagittal and coronal planes can be compared. This will be an indicator of evidence of fixator slippage [ 2,4,6,8 and 12 weeks] Extent of deformed rods, measured using visual inspection using pre and post images. [ 2,4,6,8 and 12 weeks] Evidence of any surface damage in the composite connecting rod at the clamping locations:Measured by visual inspection using pre and post images [ 2,4,6,8 and 12 weeks] [] [] [ ] [ ] [ ] [] [] [] [] [] [ ] [ ] [] [] [] [] [] [] [] [] [ ] [] [ ] [] [] [] [] [ ] [] [] [] [ ] [] [] [] [] [] [] [ ] [] [] [ ] [] [] [] [ ] [] [ ] [] [] [] [] [] [] [ ] [] [ ] [] [] [] [] [] [] [] [] [] [] [] [] [] [] [ ] [] [] [] [] [] [ ] [] [] [] [] [] [] [] [] [] [] [ ] [] [ ] [] [] [] [] [] [] [] [] [] [ ] [ ] [] [ ] [ ] [] [] [] [] [] [] [] [] [] []

Countries

Sri Lanka

Contacts

Public ContactDr. Pujitha Silva

Senior Lecturer

psilva@uom.lk

Outcome results

None listed

Source: SLCTR (via WHO ICTRP) · Data processed: Aug 9, 2026