Cerebral Palsy
Conditions
Interventions
Study Setting - Ayati, National Center for Children with Disabilities, Thalagolla Road, Ragama.
Method of Randomization - stratified randomization - based on the age of recruitment
list 1) 3-4 m
Sponsors
None
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children aged 3-6 months of age 2. Absent fidgety general movements on assessment 3. HINE (Hammesmith Infant Neurological Examination) score 40 -57 at the age of 3 - 6 months with or without abnormalities in MRI (magnetic Resonance Imaging) suggestive of an aetiology contributing towards cerebral palsy 4. HINE (Hammesmith Infant Neurological Examination) with increased number of asymmetries 5. Children of families who are willing to commit to follow up till 12 months of age
Exclusion criteria
Exclusion criteria: 1. Children who have a HINE (Hammesmith Infant Neurological Examination) score less than 40 2. Children with other major neurological or medical complications e.g. severe complex heart disease, seizure disorder. 3. Children who have undergone major interventions for their primary pathology or who are on major interventions to maintain life e.g.: VP(ventriculoperitoneal) shunt, Nasogastric tube, CPAP (Continuous Positive Airway Pressure) ventilation. 4. Children who are acutely ill and medically unstable. 5. Syndromic children 6. Infants who will be followed up at other peripheral hospitals. 7. Children who are attending services in more than one clinic. 8. Children with planned surgery or medical changes during the study which may affect their motor function
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bayley Scale of Infant Develpment vesion 111 - cognitive and motor outcome [baseline measurements will be taken at 3-6 months and after 6 months of intervention, i.e 9-12 months of age. ] | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. GMFM (Gross Motor Function Measure ): a standard assessment to evaluate the motor skills in children with cerebral palsy 2. HINE (Hammersmith Infant Neurological Examination): a neurological assessment including motor postures and reflexes in infants more than 3 months. [baseline measurements will be taken at 3-6 months and after 6 months of intervention 9-12 months of age. ] Canadian Occupation performance Measure - parent perception of performance of the child [ baseline measurements will be taken at 3-6 months and after 6 months of intervention, i.e 9-12 months of age. ] | — |
Countries
Sri Lanka
Contacts
Public ContactThilini Madushika
Research Assistant
Outcome results
None listed