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Anti-urolithic effect of selected local fruits on serum and urinary biomarkers in patients with urolithiasis: A Randomized Controlled Trial

Dietary behavior of patients with urolithiasis and antiurolithic effects of selected local fruits

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
SLCTR
Registry ID
SLCTR/2019/031
Enrollment
Unknown
Registered
2019-09-17
Start date
2019-11-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urolithiasis

Interventions

* Eight different local fruit types [Thambili ( Cocos nucifera), Hen-Kekiri ( Cucumis melovar conomon), Delum ( Punica granatum), Annasi ( Ananas comosus), Pipincha/Thiyambara ( Cucumis sativus Pi

Sponsors

Faculty of Medicine, University of Ruhuna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: For Groups 1 and 2 • Age 20 to 70 years • Male or Female • Diagnosed with urolithiasis at the Urological and General Surgical Units (defined and confirmed by the imaging studies) For Groups 3 and 4 • Age 20 to 70 years • Male or Female • Patients without urolithiasis (negative imaging studies)

Exclusion criteria

Exclusion criteria: • Patients with major illnesses such as renal failure, acute infections including acute urinary tract infections (eg: payelonephritis), carcinoma, diabetes mellitus • Unstable patients (Patients who are unstable mentally (patients with psychiatric disorders and dementia) or physically (bedridden patients)

Design outcomes

Primary

MeasureTime frame
1. Urine leukocytes, erythrocytes, nitrite and protein to exclude the presence of urinary tract infection (at baseline only) using the Dipstick test [At the baseline and at 15th day after the commencement of the intervention ] 2. Urine pH by using pH meter [At the baseline and at 15th day after the commencement of the intervention ] 3. Specific gravity by the urine strip test [At the baseline and at 15th day after the commencement of the intervention ] 4. Citrate, tartaric acid (tartrate), uric acid, oxalate, creatinine, phosphorus in urine using the spectrophotometric assay kits. [At the baseline and at 15th day after the commencement of the intervention ] 5. Presence of urinary crystals will be examined by light microscopic methods [At the baseline and at 15th day after the commencement of the intervention ] 6. Sodium, potassium in urine will be estimated by Ion Selective Electrode automated analyzers [At the baseline and at 15th day after the commencement of the intervention ] 7. Ionized calcium (or total calcium + albumin), magnesium, citrate, tartaric acid (tartrate), uric acid, oxalate, creatinine, phosphorus in serum using spectrophotometric assay kits. [At the baseline and at 15th day after the commencement of the intervention ] 8. Sodium, potassium in serum will be estimated by Ion Selective Electrode automated analyzers [At the baseline and at 15th day after the commencement of the intervention ]

Secondary

MeasureTime frame
None []

Countries

Sri Lanka

Contacts

Public ContactDr. C. M. Wickramatilake

Senior Lecturer

chandimadhu@live.com091 2234801

Outcome results

None listed

Source: SLCTR (via WHO ICTRP) · Data processed: Aug 9, 2026