Hypertension
Conditions
Interventions
The study setting will be a teaching hospital in South India
The patients will be randomized according to computer generated randomization tables in blocks of 5
The control arm will receive IV ligno
Sponsors
Vinayaka Missions Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1. Males and females under the age limit of 60 years 2. Undergoing elective surgery requiring general anaesthesia 3. Hypertensive patients on antihypertensive medications with BP (blood pressure) less than or equal to 160/90 mmHg
Exclusion criteria
Exclusion criteria: 1. Uncontrolled hypertension defined as blood pressure above 160/90 mmHg 2. Significant cardiorespiratory illness such as IHD, left heart failure, severe COPD and cor pulmonale 3. Psychiatric medication including sedative intake (Tricyclic antidepressants, Selective serotonin reuptake inhibitors, Serotonin and norepinephrine reuptake inhibitors)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Change in pulse rate 2. Change in mean arterial pressure [Immediately after Intubation] | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Laryngospasm 2. Arrthymias 3. Time taken for patients to respond to verbal commands from the termination of general anaesthesia [Outcomes 1 and 2 will be assessed immediately after anaesthesia Outcome 3 will be assessed every 5 minutes till the patient responds to verbal commands] | — |
Countries
India
Contacts
Public ContactPrasanna Vadhanan
Professor
Outcome results
None listed