Post operative respiratory complications after CABG surgery
Conditions
Interventions
Study setting: National Hospital Sri Lanka (NHSL)
All patients who admit for CABG surgery in Cardiothoracic Units of NHSL will be consecutively screened for eligibility. Following recruitment, partic
Sponsors
University of Colombo
Eligibility
Inclusion criteria
Inclusion criteria: Male and female patients between 40 to 70 years of age awaiting CABG surgery at NHSL
Exclusion criteria
Exclusion criteria: Exclusion criteria at point of recruitment 1. Other cardiovascular surgical procedure other than CABG Had a myocardial infarction within the past five days 2. Unstable angina 3. Patients with previous open heart surgery 4. Patients with hemodynamic instability –Blood pressure (BP) less than 110-70 mmHg, Heart rate 100-60, sinus rhythm 5. Uncooperative patients 6. Inability to consent or understand 7. Cognitive impairment 8. Diagnosed with cerebrovascular, orthopedic, neurologic, or cognitive-emotive disorders that would prevent the completion of the pre-surgical test items 9. Patients with COPD and any respiratory conditions 10. Any contraindication to use of PEP therapy e.g. severe haemoptysis, pneumothorax Exclusion criteria at point of analysis 11. ICU time > 72 hours 12. Depend on mechanical ventilator for more than 24 hours 13. Need balloon pump more than 24 hours 14. Need ionotropic support more than 3 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of post-operative pulmonary function over baseline as determined by 1. Forced vital capacity (FVC) 2. Forced expiratory volume in 1st second(FEV1) 3. Vital Capacity (VC) [All primary outcomes will be measured 1. Three days before surgery- baseline data 2. One week after surgery 3. One month after surgery 4. Three months after surgery 5. Six months after surgery ] | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. improvement of arterial oxygen saturation (SpO2) over baseline using pulse oximeter 2. Improvement of hand grip strength (kg) over baseline using the Jammar hand held dynamometer 3. Postoperative sternotomy incision pain using a 10 point numerical scale 4. Quality of life using the SF36 questionnaire 5. Assessment of exercise capacity using the 6 minute walk test [All secondary outcomes will be measured 1. Three days before surgery- baseline data 2. One week after surgery 3. One month after surgery 4. Three months after surgery 5. Six months after surgery ] | — |
Countries
Sri Lanka
Contacts
Public ContactMs. MDC Silva
Lecturer (Probationary)
Outcome results
None listed