Type 2 diabetes mellitus
Conditions
Interventions
The intervention will be conducted at the University of Colombo, Sri Lanka (Gymnasium and Allied Health Sciences Unit Faculty of Medicine).
The study will have 2 intervention groups (A, B) and a cont
Sponsors
University Grants Commission
University of Colombo
Eligibility
Inclusion criteria
Inclusion criteria: 1. Males and females aged 35-60 years. 2. Sri Lankan origin. 3. Diagnosed with type 2 diabetes mellitus within the last 6 years.
Exclusion criteria
Exclusion criteria: 1. Blood Glycosylated hemoglobin (HbA1c) levels 11.5%. 2. History of significant cardiovascular (ischemic heart disease etc.), respiratory (asthma, chronic obstructive pulmonary disease etc) or musculoskeletal diseases (osteoarthritis of major joints etc). 3. On insulin or thiazolidinedione therapy/other than standard oral hypoglycemic agents (metformin / sulfonylureas.). 4. Any advanced diabetes induced end-stage organ damage (vascular, retinopathy, nephropathy, neuropathy, retinal hemorrhage or detachment, history of laser therapy). 5. People with a cognitive impairment, an intellectual disability, or a mental illness. 6. Current participation in supervised Resistance Training or Aerobic Training. 7. Engaged in Resistance Training in previous 6 months. 8. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Absolute change in HbA1c 2. Absolute change in total body fat percentage values [measured using Dual energy x ray absorptiometry (DEXA) full body scan]. [At baseline, and at the end of 12 weeks (following 24 exercise sessions). ] | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Plasma lipid profile 2. Liver profile 3. Muscle strength:Percentage (%) change in One Repetition Maximum (1RM). 4. Lean mass: Dual energy x ray absorptiometry (DEXA) full body scan. 5. Blood pressure 6. Cardiovascular endurance: McArdle Step test and YMCA cycle ergometer test. 7. Quality of life: SF-36 quality-of-life outcomes questionnaire 8. Change in food preference measured by the Leeds Food Preference Questionnaire (LFPQ) [Outcomes 1-7 will be assessed at baseline and at the end of the 12 weeks of intervention. Outcome 8 will be assessed pre-and post-exercise session at baseline and at the final session (end of 12 weeks). ] | — |
Countries
Sri Lanka
Contacts
Public ContactDilip Chathuranga Ranasinghe
Lecturer
Outcome results
None listed