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Inactivated Polio Vaccine (IPV) Mucosal Immunity Boosting Trial in Kalutara District, Sri Lanka 2016

Inactivated Polio Vaccine (IPV) Mucosal Immunity Boosting Trial in Kalutara District, Sri Lanka 2016

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
SLCTR
Registry ID
SLCTR/2016/010
Enrollment
Unknown
Registered
2016-04-01
Start date
2016-04-18
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polio virus immunity

Interventions

The study will be carried out at field settings, in 3 MOH areas in the Kalutara district. Participants meeting inclusion/exclusion criteria will be allocated into 3 arms using block randomization Arm

Sponsors

World Health Organization Head Quarters
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children aged 10-12 years 2. Residence in the selected areas of the Kalutara District 3. Parent/Guardian provides consent for child’s participation

Exclusion criteria

Exclusion criteria: 1. Contraindication for venipuncture 2. Sick child requiring hospitalization for acute or chronic illness 3. Diagnosis or suspicion of congenital immunodeficiency disorder in the subject or an immediate family member

Design outcomes

Primary

MeasureTime frame
Polio immunity as determined by IgG antibody levels (blood) [IgG antibodies in blood: day 0 and day 30 following IPV] Polio virus excretion rates (stools) [Polio virus excretion in stools: day 30 following IPV as a baseline, and then day 3, day 7 and day 14 following OPV] Duration of polio virus excretion (stools) [ ]—

Secondary

MeasureTime frame
None [None]—

Countries

Sri Lanka

Contacts

Public ContactDeepa Gamage

Consultant Epidemiologist

deepagamage@gmail.comTel: 0112695112

Outcome results

None listed

Source: SLCTR (via WHO ICTRP) · Data processed: Aug 9, 2026