A study to determine the palatability of different dosage forms of oral N-Acetylcysteine and methionine among healthy volunteers

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

SLCTR

Registry ID

SLCTR/2016/001

Enrollment

Registered

2016-01-19

Start date

2016-01-24

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Palatability of antidotes to paracetamol poisoning

Interventions

The study will be carried out at the South Asian Toxicology Research collaboration, Faculty of Medicine, University of Peradeniya. Undergraduates of the University of Peradeniya who are not enrolled

Eligibility

Inclusion criteria

Inclusion criteria: 1. Healthy male and female volunteers (who are not medical students) 2. Age 19-26 years

Exclusion criteria

Exclusion criteria: 1. Condition or dietary habit known to interfere with the sense of smell and taste 2. Ingestion of any other medication within 48 hours 3. Significant illness within the previous two weeks 4. History of autonomic dysfunction 5. Atopic allergy 6. Known hypersensitivity to any drug 7. Pregnancy or breast feeding

Design outcomes

Primary

Measure	Time frame
Each of the following outcomes will be scored on a modified 100 mm visual analogue scale. 1.1.Smell 1.2.Taste 1.3.Ease of swallowing 1.4. After taste 1.5. Adverse events within one hour [Just after the administration up to one hour]	—

Secondary

Measure	Time frame
None [None]	—

Countries

Sri Lanka

Contacts

Public ContactProf. Indika Gawarammana

Professor in Medicine

indikagaw@gmail.com0814479822

Outcome results

None listed

Source: SLCTR (via WHO ICTRP) · Data processed: Aug 9, 2026