A study on therapeutic efficacy of the herbal decoction Rasna sapthakya in patients with rheumatoid arthritis

A phase II/III study of the anti-inflammatory activity of Rasna sapthakaya decoction in patients with rheumatoid arthritis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

SLCTR

Registry ID

SLCTR/2015/028

Enrollment

Unknown

Registered

2015-11-30

Start date

2015-12-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhematoid arthritis

Interventions

The seven constituents of Rasna Sapthakaya (RS) decoction are Alpinia calcarata - root Tinospora cordifolia- stem Cassia fistula- bark of the root Boerhavia diffusa- root Ced

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with rheumatoid arthritis, of either sex diagnosed according to the American College of Rheumatology (ACR) criteria for classification of Rheumatoid arthritis (RA) 2. Those who have no history of drug allergy (Ayurvedic or Western).

Exclusion criteria

Exclusion criteria: 1. Those who are receiving any other anti- inflammatory drugs (Western /Ayurveda) 2. Pregnancy 3. Breast feeding

Design outcomes

Primary

Measure	Time frame
1. Full blood count 2. ESR 3. Rheumatoid factor (RF) 4. Serum anti cyclic citrulinated peptide (Anti-CCP) antibody 5. Serum cyclo-oxygenase 2 (COX 2) 6. Presence of fever 7. Odema (measured at predetermined location using a standard measuring tape 8. Joint mobility (using a goniometer) [At baseline, day 15 and day 56 (end of two months)]	—

Secondary

Measure	Time frame
Selected side effects as recorded in a patient diary, including headache, nausea, vomiting, diarrhoea and allergic reactions ( itching, sneezing) [At baseline, day 15 and day 56 (end of two months)]	—

Countries

Sri Lanka

Contacts

Public ContactDr.J.M. Dahanayake

Senior Lecturer

jdahanayake@yahoo.com

Outcome results

None listed

Source: SLCTR (via WHO ICTRP) · Data processed: Aug 9, 2026