Therapeutic evaluation of a Ayurveda drug preparation Sudarshana suspension in febrile children

Therapeutic evaluation of the antipyretic activity of the Ayurvedic preparation Sudarshana Suspension in febrile children.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

SLCTR

Registry ID

SLCTR/2015/026

Enrollment

Unknown

Registered

2015-11-19

Start date

2015-11-20

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fever

Interventions

Patients with fever, between 6-12 years out of the admitted patients to the hospital and from the Out Patient Department (OPD) of Paediatrics clinics at the Ayurvedic Teaching Hospital, Borella, will

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children of either sex aged 6- 12 years at the time of enrollment 2. Axillary temperature of 37. 5°C or above at arrival and/or after one hours observation 3. No other antipyretic medication given 4. Admitted by parents or legal guardians who can write and read English or Sinhala 5. Only patients with fever with no other signs and symptoms of systemic illness

Exclusion criteria

Exclusion criteria: 1. Weight below the third centile for age 2. Those receiving anticoagulant treatment 3. History of intolerance to Sudarshana powder or similar compounds 4. Previous occurrence or current symptoms of peptic ulceration or gastrointestinal bleeding 5. Diagnosis of severe liver, heart, kidney, or systemic disease including malignancy 6. On other medication which needs to be taken during the study or in the six hours prior to recruitment 7. Those receiving any other antipyretic or anti inflammatory drugs. 8. Any history of drug allergy.

Design outcomes

Primary

Measure	Time frame
1.Therapeutic effect of the medications within the first 6 hours using a five point scale: 0= no effect (fever does not resolve) 1= fever resolves completely within 6 hours 2= fever resolves completely within 5 hours 3= fever resolves completely within 3 hours 4= fever resolves completely within 2 hours 5= very good effect (fever resolves completely within 1 hour) 2.Overall therapeutic effect of the medication will be recorded on a four point scale: 0= no effect (No change in the body temperature) 1= fever resolves completely within 72 hours 2= fever resolves completely within 48 hours 3= fever resolves completely within 24 hours 4= very good effect (fever resolves completely within 6 hours ) [1. Within the first 6 hours following administration 2. At the end of three days or at complete resolution of the fever. ]	—

Measure

Time frame

1.Therapeutic effect of the medications within the first 6 hours using a five point scale: 0= no effect (fever does not resolve) 1= fever resolves completely within 6 hours 2= fever resolves completely within 5 hours 3= fever resolves completely within 3 hours 4= fever resolves completely within 2 hours 5= very good effect (fever resolves completely within 1 hour) 2.Overall therapeutic effect of the medication will be recorded on a four point scale: 0= no effect (No change in the body temperature) 1= fever resolves completely within 72 hours 2= fever resolves completely within 48 hours 3= fever resolves completely within 24 hours 4= very good effect (fever resolves completely within 6 hours ) [1. Within the first 6 hours following administration 2. At the end of three days or at complete resolution of the fever. ]

—

Secondary

Measure	Time frame
Palatability of medications using a five point scale [Immediately following the first dose and at the end of 6 hours]	—

Countries

Sri Lanka

Contacts

Public ContactDr. W.A.S.S. Weerakoon

Lecturer and Consultant Ayurvedic Paediatrician

sarojaweerakoon@yahoo.comTel: 0112694308

Outcome results

None listed

Source: SLCTR (via WHO ICTRP) · Data processed: Aug 9, 2026