Blood glucose response to commonly consumed herb
Conditions
Interventions
The subjects will be recruited from the staff of the University of Peradeniya. The Principle investigator will approach eligible subjects and inform and screen them. Subjects will be randomized using
Sponsors
Department of Medicine
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy male and females aged between 18-65 years, 2. Fasting plasma glucose <100mg/dl following a 10- hour fast
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating females 2. Inability to give informed written consent 3. Known hypersensitivity to Costus specious 4. Presence of T2DM, CKD, CCF, elevated hepatic transaminases, blood dyscrasia, malignancies 5. Current steroid therapy 6. Treatment with any oral hypoglycaemic agent (taken for indications other than DM as well), 7. Known intestinal diseases, malabsorptive states and diarrhoea. 8. Ingestion of any herbal preparation (including C. speciosus) known to alter glucose metabolism within the 48 hours preceding test meal administration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. 2-Hour plasma glucose following the meal 2. 4 hour plasma glucose following the meal 3. Fasting plasma glucose the following morning [1.2 hours following the test meal 2.4 hours following the meal 3.Fasting plasma glucose the following morning after a fast of 8-10 hours. ] | — |
Secondary
| Measure | Time frame |
|---|---|
| None [None] | — |
Countries
Sri Lanka
Contacts
Public ContactArjuna Medagama
Senior Lecturer in Medicine
Outcome results
None listed