A study of the Ayurvedic preparation Rasna Sapthakaya decoction in healthy volunteers

A phase I study of the possible toxicity of the Ayurvedic preparation, Rasna Sapthakaya

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

SLCTR

Registry ID

SLCTR/2015/006

Enrollment

Registered

2015-03-02

Start date

2015-03-02

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic arthritis (proposed indication)

Interventions

The seven constituents of Rasna Sapthakaya decoction are

1. Alpinia calcarata - root 2. Tinospora cordifolia- stem 3. Cassia fistula- bark of the root 4. Boerhavia diffusa- root 5. Cedrus deodara – wood 6. Ricinus communis - root 7. Tribulus testre

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age group of 18-60 years at the time of enrollment, of either sex 2. No diagnosed chronic disorders such as hypertension, diabetes mellitus, hypercholesterolaemia, chronic arthritis 3. No history of drug allergy (Ayurvedic or Western).

Exclusion criteria

Exclusion criteria: 1. Use of Those who are receiving any other anti- inflammatory drugs. 2. Pregnancy 3. Breast feeding

Design outcomes

Primary

Measure	Time frame
Serum Alanine transferase (ALT) [At baseline, Day 8 and Day 15] Serum Aspartate transferase (AST) [At baseline, Day 8 and Day 15 ] Serum Alkaline phosphatase (ALP) [At baseline, Day 8 and Day 15 ] Serum creatinine [At baseline, Day 8 and Day 15 ] Blood urea [At baseline, Day 8 and Day 15 ]	—

Secondary

Measure	Time frame
Selected side effects as recorded in a patient diary, including headache, nausea, vomiting, diarrhoea and allergic reactions ( itching, sneezing) [At baseline, Day 8 and Day 15]	—

Countries

Sri Lanka

Contacts

Public ContactMrs. Rajavarthani Sanjeev

Lecturer

r_varthani@yahoo.com

Outcome results

None listed

Source: SLCTR (via WHO ICTRP) · Data processed: Aug 9, 2026