Fever (proposed indication)
Conditions
Interventions
Healthy adult volunteers will be recruited by an open advertisement displayed in the notice boards of the University of Sri Jayewardenepura and Institute of Indigenous Medicine, University of Colombo.
Sponsors
HETC Project, Ministry of Higher Education
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age group of 18-60 years at the time of enrollment, of either sex with weight less than 60kg 2.Those who have no known systemic disorders, such as hypertension, diabetes mellitus, hypercholesterolemia and chronic arthritis 3. Those who have no history of drug allergy. 4.Those who have no history of intolerance to Sudarshana Powder or similar compounds 5. Women should be non pregnant and non breast feeding. 6. Only those who can write and read languages of English or Sinhala.
Exclusion criteria
Exclusion criteria: Concurrent treatment with any Ayurveda or Western medicine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the following bio-markers 1. Alanine aminotransferase (ALT) 2. Aspartate aminotransferase (AST) 3. Gamma-glutamyl transferase (Gamma-GT) 4. Alkaline phosphatase 5. Haemoglobin (Hb) 6. Urea in serum 7. Serum Creatinine Volunteers will be requested to maintain the diary recording noting the time of drug administration, any unusual symptoms (vomiting, headache, diarrhoea) and time of onset and duration of the symptoms during the treatment period and follow up period. [In each subject, basic epidemiological and anthropometric data (age, sex, weight) including visit check list will be recorded by the principal investigator and also the volunteer diary will be recorded by the volunteer ] | — |
Secondary
| Measure | Time frame |
|---|---|
| After successive intervention of phase I , phase II studies will be planned according to ERC approval. [At baseline, day 3 and day 8] | — |
Countries
Sri Lanka
Contacts
Public ContactDr. W.A.S.S.Weerakoon
Lecturer and Consultant Ayurvedic Paediatrician
Outcome results
None listed