Chronic diabetic wounds
Conditions
Interventions
Participants will be recruited from in-ward patients as well as patients attending the wound clinics of the Colombo South Teaching Hospital. Consenting participants will be randomized into three arms.
Sponsors
Department of Surgery
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age over 18 years 2. Chronic diabetic wounds which have lasted over 1 month 3. No clinical evidence of occlusive arterial disease
Exclusion criteria
Exclusion criteria: 1. Uncontrolled diabetes needing inward management 2. Clinical evidence of concurrent occlusive arterial disease (OAD). 3. Other co-morbidities requiring use of systemic antibiotics 4. Any patient needing surgical intervention or use of other methods (rotational antiseptics) to control wound infection. I 5. Known hypersensitivity to acetic acid or ascorbic acid
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound healing according to PEDIS score (Perfusion, Extent/size, Depth/tissue loss, Infection, and Sensation) and an objective wound assessment questionnaire [At baseline, at the end of one week and at the end of 1 month] | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Bacterial colony count of the wound 2. pH of the wound [Both secondary outcomes will be assessed at the following time points. Day 1: Pre swab (prior to antiseptic instillation), 10 minutes after instillation, 1 hour after instillation, 4 hours after instillation Day 3: Pre swab (prior to antiseptic instillation), 10 minutes after instillation, 1 hour after instillation, 4 hours after instillation At the end of one month ] | — |
Countries
Sri Lanka
Contacts
Public ContactDr. Thilina Samarasinghe
Outcome results
None listed