Induction of labour
Conditions
Interventions
Consenting participants meeting inclusion/exclusion criteria will be allocated to four arms using block randomization. All the induction methods will be carried out from 40+4 weeks of gestation onwar
Sponsors
New unit for Obstetrics and Gynaecology
Eligibility
Inclusion criteria
Inclusion criteria: 1. Multiparous women undergoing induction of labour at the study setting. 2. Gestation more than 40+4 weeks 3. Singleton pregnancy with cephalic presentation 4. Unruptured membrane 5. Modified Bishop Score (MBS) less than 8
Exclusion criteria
Exclusion criteria: 1. Primiparity 2. Malpresentation and unstable lie. 3. Favourable cervix (MBS of 8 or above) 4. Any contraindication to vaginal birth, with previous uterine surgery (including caesarean section, placenta previa and other placental anomalies) 5. Age less than 18 years 6. Lethal fetal congenital anomaly 7. Known allergy to any of the interventional products
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Time interval between induction of labour to vaginal delivery 2. Rates of failed induction (needing caesarian section or second induction method) [Up to 72 hours after induction of labour . ] | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Requirement for oxytocin augmentation 2. Incidence of uterine hyperstimulation 3. Incidence of intrapartum fetal blood sampling 4. Mode of delivery 5. Blood loss at delivery 6. Incidence of maternal pyrexia (>37.3°C), 7. Perineal lacerations require suturing, 8. APGAR score at 1 minute and 5 minutes 9. Need for admission to a neonatal intensive care unit (NICU). [Up to 72 hours after induction of labour] | — |
Countries
Sri Lanka
Contacts
Public ContactDr.P.D.M.Pathiraja
Registrar in Obstetrics and Gynaecology
Outcome results
None listed