Clomiphene Citrate vs Letrozole in the treatment of anovulatory infertility

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

SLCTR

Registry ID

SLCTR/2014/009

Enrollment

Registered

2014-04-25

Start date

2014-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anovulatory infertility

Interventions

Patients attending to the subfertility clinic will be recruited. Tubal patency will be diagnosed by doing a hysterosalpingogram or a laparoscopy and chromotubation. Selected females will be randomiz

Eligibility

Inclusion criteria

Inclusion criteria: • Females < 40 years • Infertile ( inability to achieve a pregnancy after a one year of regular unprotected sexual intercourse.) • Anovulatory - diagnosed by assessing mid-luteal progesterone levels and assessment of follicular development by serial trans-vaginal ultrasound scanning • Proven tubal patency

Exclusion criteria

Exclusion criteria: • Females having tubal factor infertility • Females whose partners have male factor subfertility

Design outcomes

Primary

Measure	Time frame
Follicular development assessed bytrasvaginal ultrasound scan [12th day of the cycle]	—

Secondary

Measure	Time frame
1. Number of mature follicles (>18mm diameter) 2. Pregnancy 3. Endometrial thickness on the day of hCG administration 4. Multiple pregnancy rate 5. Miscarriage rate [1. 12th day of cycle 2. After missed period (early 1st trimester) 3.12th day of cycle 4.First trimester 5.First trimester ]	—

Countries

Sri Lanka

Contacts

Public ContactDr. M C Gihan

Lecturer in Obstetrics & Gynaecology, Faculty of Medicine, University of Peradeniya and Registrar inObstetrics & Gynaecology

champikagihan@yahoo.com

Outcome results

None listed

Source: SLCTR (via WHO ICTRP) · Data processed: Aug 9, 2026