Study on the use of oxytocin bolus and infusion to prevent blood loss during caesarean section

Effectiveness of 5-IU oxytocin bolus and 20 IU infusion compared to 5-IU oxytocin bolus and placebo infusion in the control of blood loss during and after ante-partum lower segment caesarean section.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

SLCTR

Registry ID

SLCTR/2013/019

Enrollment

Registered

2013-05-29

Start date

2013-05-29

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood loss during and after caesarean section

Interventions

Consenting participants will be randomized into 2 arms. Women in the intervention arm will receive a 5IU IV bolus of oxytocin will be given over 5–10 s to each women when the umbilical cord was clampe

Eligibility

Inclusion criteria

Inclusion criteria: 1. Women aged 15-45 years 2. Women delivering via an elective caesarean section at term

Exclusion criteria

Exclusion criteria: 1. Multiple pregnancies 2. Chorioamnionitis 3. History of post partum haemorrhage 4. Clotting disorder 5. Uterine fibroids 6. Placenta praevia 7. Placental abruption

Design outcomes

Primary

Measure	Time frame
Mean blood loss in mililiters 2. Post partum haemorrhage (no PPH -500-1000ml -1000-3000ml ->3000ml) 3. Maternal Hb and PCV 4. Need for blood transfusion 5. Need for therapeutic uterotonics [1. During and after surgery 2. During and after surgery 3. Pre-operatively and at 48 hours post-operatively 4. Intra-operatively and up to 48 hours post-operatively 5. Up to 48 hours post operatively ]	—

Secondary

Measure	Time frame
None [None]	—

Countries

Sri Lanka

Contacts

Public ContactDr.J.Kajendran

Registrar (Obstetrics & Gynaecology)

kajendranj@yahoo.com

Outcome results

None listed

Source: SLCTR (via WHO ICTRP) · Data processed: Aug 9, 2026