Chronic Kidney Disease (of unknown etiology)
Conditions
Interventions
Paste of dried Melothria maderaspatana (Titta kekiri) and Passiflora foetida (Dal batu) will be applied for 6 hours daily to the big toe of test group for a period of 10 months. Placebo paste will be
Sponsors
Faculty of Medicine University of Rajarata
Eligibility
Inclusion criteria
Inclusion criteria: a)Diagnosed patients of having grade II and III CKDu, Normal HbA1C (?6.5%) and BP?160/100 mmHg untreated or ?140/90 mmHg on up to two antihypertensive agents, Persistent albuminuria + eGFR 30- 89 mi/min/1.73m2 b)Age between 20-60 years c)Permanent residents of Anuradhapura or Polonnaruwa district, for at least 5 years prior to diagnosis as Grade II or III CKDu
Exclusion criteria
Exclusion criteria: a)Patients with no past history of or current treatment for diabetes mellitus or chronic and/or severe hypertension, snakebite, urological disease of known etiology or glomerulonephritis b)Patients who are suffering with other chronic diseases or on treatment for any other disease other than CKDu c)Patients aged less than 20 years and more than 65 years d)Pregnant and breast feeding mothers e)Patients who live outside the NCP,are not permanent resident within NCP at least 5 years prior to diagnose as CKDu and residents in GN divisions where WHO is conducting the Study for CKDu
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Full blood count [10 months] Lipid profile [10 months ] Renal profile [10 months ] Liver enzymes-SGPT and SGOT [10 months ] Urine full report including ß2 globulin level [10 months ] IFNd [10 months ] TNFa [10 months ] HSP70 [10 months ] | — |
Secondary
| Measure | Time frame |
|---|---|
| None [None] | — |
Countries
Sri Lanka
Contacts
Public ContactDr. M.A.C.S.Jayasumana
Lecturer in Pharmacology
Outcome results
None listed