Snakebites requiring antivenom administration
Conditions
Interventions
Patients will be randomly allocated to two groups and one will receive antivenom dose over 20 minutes while the others will receive the same dose over 2 hours.
Sponsors
IRQUE Project
Eligibility
Inclusion criteria
Inclusion criteria: Patients with a possible clinical diagnosis of a snakebite
Exclusion criteria
Exclusion criteria: * Under 14 years of age * Pregnant ladies * Previous administration of antivenom * Refusal of consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion with severe systemic allergic reactions within 4 hours of commencement of antivenom [within 4 hours of commencement] | — |
Secondary
| Measure | Time frame |
|---|---|
| * Proportion with elevated mast cell tryptase * Proportion with elevated antivenom specific IgE * Hospital length of stay * Proportion with mild allergic reactions * Proportion with delayed administration of -further antivenom therapy * Proportion developing serum sickness [] | — |
Countries
Sri Lanka
Contacts
Public ContactDr. Ariaranee Gnanathasan
Senior Lecturer
Outcome results
None listed