Overweight and obesity
Conditions
Interventions
Group A (Experimental): 80 g of goat cheese with lower content of fat three days a week for fourth weeks, prohibited consuming milk, yogurt, cheese.
Group B (Control): 80 g of goat cheese with higher
Diet, Food, and Nutrition
goat cheese
Sponsors
Genomic Biotechnology Center – National Polytechnic Institute (IPN-Reynosa), Mexico
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Adults: Women and Men 2. Nationality of any kind 3. Body mass index =25 4. Age: 18–55 years 5. Clinically healthy 6. Subjects from any socioeconomic or cultural group 7. Able to be informed about the study and willing to accept and sign written informed consent prior to the study 8. Consume goat cheese
Exclusion criteria
Exclusion criteria: 1. Allergic and/or lactose intolerant 2. Type I or II diabetes 3. High blood pressure (defined as systolic blood pressure =140 or diastolic blood pressure =90 mmHg) 4. Cardiovascular disease, chronic kidney disease 5. Hyperlipidemia 6. Alcoholism and/or drug dependence 7. Smoker (>10 cigarettes per day) 8. Women who are pregnant or breastfeeding 9. Undergoing any medical treatment 10. Use of anorectic agents that act on the adrenergic, serotonergic, and adrenergic/serotonergic pathways. 11. Use of medications or supplements. 12. Insufficient motivation, as assessed by the interview, to remain in the clinical trial. 13. The volunteer no longer wishes to participate in the study 14. Inability to comply with the instructions of the investigation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acylated ghrelin. Measurement time: At the beginning and 4 weeks (before breakfast, at minute 30 and 120 after finishing breakfast). | — |
Secondary
| Measure | Time frame |
|---|---|
| Anthropometric measurements and indexs: Weight (in Kg), Waist circumference (in cm), Abdominal circumference (in cm), Hip circumference (in cm), Waist-hip ratio (waist circumference/hip circumference in cm), Body Mass Index-BMI (Weight/(Height*Height). (Weight measured in Kg and height in m) measurement time: At baseline, at 2 and 4 weeks. Satiety (VAS) Measurement time: before breakfast, at minute 30 and 120 after finishing breakfast. Bacterial diversity Measurement time: at baseline, at 2, 3 and 4 weeks. Plasma lipid profile (Total cholesterol, Triglycerides, very low, low and high density lipoproteins (values in mg/dL)), measurement time: At baseline and 4 weeks. Nutrigenetic and nutrigenomic analysis measurement time: At baseline and 4 weeks. HOMA-IR index, measurement time: At baseline and 4 weeks. | — |
Countries
Mexico
Contacts
Public ContactDiana Vela Vasquez
Genomic Biotechnology Center – National Polytechnic Institute
Outcome results
None listed