Prebiotics and probiotics in the treatment of type 2 diabetes

Effect of BiotiQuest™ Sugar Shift and Kesto Mix dietary supplements in the treatment of type 2 diabetes mellitus (T2DM).

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

RPCEC

Registry ID

RPCEC00000413

Enrollment

150

Registered

2022-12-06

Start date

2021-06-25

Completion date

Unknown

Last updated

2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes Mellitus

Interventions

Group 1 - BiotiQuest™ Sugar Shift Probiotic Capsules (Experimental): One capsule will be administered orally every 12 hours for 12 weeks. Each capsule contains 96 mg (18 billion CFU) of a bacterial co

Dietary Supplements

Probiotics

Prebiotics

Tablets

Placebos

Dietary Supplements BiotiQuest™ Sugar Shift and Kesto Mix

Eligibility

Sex/Gender

All

Age

30 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age from 30 to 65 years (both inclusive), of any gender or skin color 2. Patients with a clinical diagnosis of DM2 3. Able and willing to give informed written consent.

Exclusion criteria

Exclusion criteria: 1. Patients with chronic kidney disease, oncoproliferative diseases and pregnant women. 2. Patients with intellectual or psychological dysfunction that does not allow the understanding and compliance with the requirements of the study, according to the criteria of the Principal Investigator.

Design outcomes

Primary

Measure	Time frame
Glycosylated hemoglobin A1c (Hb-A1c) (values ??in %). Measurement time: Day 1 and 84.	—

Secondary

Measure	Time frame
Fasting glucose (values ??in mmol/L obtained from samples of serum). Measurement time: Day 1, 28, 56 and 84. Postprandial glucose (2h) (values ??in mmol/L obtained from samples of serum). Measurement time: Day 1, 28, 56 and 84. Cholesterol (values ??in mmol/L obtained from serum samples). Time of measurement: Day 1 y84. Triglycerides (values ??in mmol/L obtained from serum samples). Time of measurement: Day 1 and 84. HDLc (values ??in mmol/L obtained from serum samples). Time of measurement: Day 1 and 84. LDLc (values ??in mmol/L obtained from serum samples). Time of measurement: Day 1 and 84. Insulin (values ??in mIU/mL obtained from serum samples). Time of measurement: Day 1 and 84. Creatinine (values ??in µmol/L obtained from serum samples). Time of measurement: Day 1 and 84. LPS (Endotoxin Units/mL obtained from serum samples). Time of measurement: Day 1 and 84. Microbiome analysis (values ??in mIU/mL obtained from feces). Time of measurement: Day 1 and 84.	—

Measure

Time frame

Fasting glucose (values ??in mmol/L obtained from samples of serum). Measurement time: Day 1, 28, 56 and 84. Postprandial glucose (2h) (values ??in mmol/L obtained from samples of serum). Measurement time: Day 1, 28, 56 and 84. Cholesterol (values ??in mmol/L obtained from serum samples). Time of measurement: Day 1 y84. Triglycerides (values ??in mmol/L obtained from serum samples). Time of measurement: Day 1 and 84. HDLc (values ??in mmol/L obtained from serum samples). Time of measurement: Day 1 and 84. LDLc (values ??in mmol/L obtained from serum samples). Time of measurement: Day 1 and 84. Insulin (values ??in mIU/mL obtained from serum samples). Time of measurement: Day 1 and 84. Creatinine (values ??in µmol/L obtained from serum samples). Time of measurement: Day 1 and 84. LPS (Endotoxin Units/mL obtained from serum samples). Time of measurement: Day 1 and 84. Microbiome analysis (values ??in mIU/mL obtained from feces). Time of measurement: Day 1 and 84.

—

Countries

Cuba

Contacts

Public ContactGissel Garcia Menendez

Hermanos Ameijeiras Surgical Clinical Hospital

gisselgarcia@infomed.sld.cu

Outcome results

None listed

Source: RPCEC (via WHO ICTRP) · Data processed: Aug 25, 2026