Stem cell assisted centrifugal fat transfer

Efficacy of adipose-derived stem cell-assisted fat transfer by centrifugation in facial rejuvenation. Phase III clinical trial.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

RPCEC

Registry ID

RPCEC00000362

Enrollment

Unknown

Registered

2021-03-26

Start date

2020-10-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Facial aging

Interventions

Study group: Infiltration of local anesthesia with 0.5% lidocaine, in the internal part of the navel. Infiltration of modified Klein anesthetic solution in the peri-umbilical area with a cannula with

Stem Cells

Rejuvenation

Centrifugation

Lipotransfer, Assisted centrifugation

Eligibility

Sex/Gender

All

Age

30 Years to 59 Years

Inclusion criteria

Inclusion criteria: 1. Patients between the ages of 30 and 59, without distinction of sex. 2. Patients with signs of facial aging. 3. Willingness to participate in the study, with prior written informed consent. 4. Compensated chronic diseases, if you suffer from them.

Exclusion criteria

Exclusion criteria: 1. History of psychiatric disorders or coagulopathies. 2. Patients whose expectations cannot be achieved with the procedure. 3. Pregnant or lactating women. 4. Tendency to keloid. 5. Skin or systemic infection. 6. Patients who are on anticoagulant, antifibrinolytic or non-steroidal anti-inflammatory drugs (NSAIDs) or steroids. 7. History of having made facial lipotransfer or injected other substances as fillers in the face.

Design outcomes

Primary

Measure	Time frame
Evaluation of the final result: (Good, Fair, Bad). Measurement time: 12 months after the intervention.	—

Secondary

Measure	Time frame
1. Clinical evolution of furrows and wrinkles (Clinical response to treatment interpreted by doctor and patient, using the Global Aesthetic Improvement Scale (GAIS)] (Exceptional improvement. Total disappearance of wrinkles, Much improved. Marked partial response. Decrease in the number of wrinkles between 50 and 99%, Improved. Slight partial response. Decrease in the number of wrinkles less than 50%, No response. Same as at the beginning of treatment, Progression. Increased number or size of wrinkles )). Measurement time: 12 months after the intervention. 2. Satisfaction status: (Satisfied, Not satisfied). Measurement time: 12 months after the intervention. 3. Complications (Yes, No). Measurement time: 24 and 72 hours, 1 week and, 3, 6 and 12 months after the intervention. 4. Type of complications (Describe complications that appear). Measurement time: 24 and 72 hours, 1 week and, 3, 6 and 12 months after the intervention.	—

Measure

Time frame

1. Clinical evolution of furrows and wrinkles (Clinical response to treatment interpreted by doctor and patient, using the Global Aesthetic Improvement Scale (GAIS)] (Exceptional improvement. Total disappearance of wrinkles, Much improved. Marked partial response. Decrease in the number of wrinkles between 50 and 99%, Improved. Slight partial response. Decrease in the number of wrinkles less than 50%, No response. Same as at the beginning of treatment, Progression. Increased number or size of wrinkles )). Measurement time: 12 months after the intervention. 2. Satisfaction status: (Satisfied, Not satisfied). Measurement time: 12 months after the intervention. 3. Complications (Yes, No). Measurement time: 24 and 72 hours, 1 week and, 3, 6 and 12 months after the intervention. 4. Type of complications (Describe complications that appear). Measurement time: 24 and 72 hours, 1 week and, 3, 6 and 12 months after the intervention.

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Countries

Cuba

Contacts

Public ContactAlicia Tamayo Carbon

"Hermanos Ameijeiras" Surgical Clinical Hospital

cplastica@hha.sld.cu

Outcome results

None listed

Source: RPCEC (via WHO ICTRP) · Data processed: Apr 4, 2026