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Zinc-Children-Hospitalized-Pneumonia

Zinc Sulfate as an adjuvant in a child hospitalized for pneumonia. Randomized clinical trial (ZiNiNe) - ZiNiNe

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
RPCEC
Registry ID
RPCEC00000325
Enrollment
200
Registered
2020-07-09
Start date
2017-04-06
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

community-acquired pneumonia

Interventions

Children hospitalized for pneumonia were divided into 2 groups Group I: experimental, received zinc sulfate orally 0.5% zinc syrup dose was 10 mg / day which corresponded to 2cc for children under 1
Zinc Sulfate
Placebo
Administration, Oral

Sponsors

Autonomous Service Antonio Patricio de Alcalá University Hospital (SAHUAPA)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 5 Years

Inclusion criteria

Inclusion criteria: 1.The diagnosis of pneumonia was considered in that child with fever (T ° = 38.5 ° C) in the presence of signs and symptoms such as respiratory distress, retractions or draws and cough accompanied by radiological changes.

Exclusion criteria

Exclusion criteria: The following were excluded from the study: 1. Patients with congenital malformations 2. Patients immunosuppressed by drugs or primary diseases of the immune system 3. Patients with suspected foreign body aspiration 4. Previous hospitalizations in the last 4 weeks 5. Presence of wheezing as dominant findings.

Design outcomes

Primary

MeasureTime frame
Resolution of pneumonia (Time measured in hours required to normalize the clinical elements that defined the pneumonia). Measurement time: from the moment of admission until normal

Secondary

MeasureTime frame
Remission rate of clinical indicators of pneumonia in percentage. Measurement time: at 72 hours’ intervention started 2. Therapeutic failure (Need to change the initial antibiotic, the appearance of complications or the persistence of hypoxemia). Measurement time: at 72 hours’ intervention started 3. Adverse effects (Any reaction related to the intervention). Measurement time: up to 14 days.

Countries

venezuela

Contacts

Public ContactElias Kassisse El Hage

Herminda Martin Clinical Hospital

ekassisse@gmail.com

Outcome results

None listed

Source: RPCEC (via WHO ICTRP) · Data processed: Aug 25, 2026