Acne scarring, melasm, or other injuries that require chemical peeling.
Conditions
Interventions
Group I experimental: Will peelings 1-3 sets of media to the application of trichloroacetic acid (ATA) to 20% in the facial region with intervals of 15-21 days, followed by topical administration of t
Sponsors
Center for Genetic Engineering and Biotechnology (CIGB), in Havana.
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Informed consent. 2.Age major than 20 years old, both sexes. 3.Skin diseases that affect facial aesthetics and require peel. 4.Fitzpatrick skin type classification I to IV.
Exclusion criteria
Exclusion criteria: 1.Active lesions of acne vulgaris that require treatment or patient with them in the last 6 months. 2.Fitzpatrick skin type classification V-VI. 3.Infection requiring antibiotic treatment or active herpes virus infection. 4.Another skin disease affecting the face. For example: neurotic excoriation. 5.Personal history of keloids or others defect of healing. 6.Diabetes mellitus, erythematosus lupus or some others systemic disease that concern general compliance (liver disease, renal disease, pancreatic disease, colagenosis, anemia, etc.). 7.Malignancies (except the basal cell carcinoma and the cervix cancer in situ after surgery and complete cured). 8.Serious hypertension or heart disease. 9.Previous treatment with steroids in the last 3 months. 10.Previous treatment with EGF in the last 30 days. 11.Previous treatment in the last 6 months like this: isotretinoin, chemical peels, aesthetic or surgical procedure of the head or neck. 12.Serious psychiatric disorder and other disease that limit informed consent. 13.Patient exposed to ultraviolet radiation due to their occupation. 14.Pregnancy and lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to healing, 1 month after treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of healing, one year after treatment. Adverse events during the period for completion of media peels, a month after treatment and follow-up a year. | — |
Countries
Cuba
Contacts
Public ContactDr. Pedro López Saura
Center for Genetic Engineering and Biothecnology (CIGB), in Havana.
Outcome results
None listed