Amniotic Membrane Transplantation vs Conjunctival–Limbal Autograft for Primary Pterygium

Amniotic Membrane Transplantation vs Conjunctival–Limbal Autograft , for Primary Pterygium. Randomized, blind controlled trial.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

RPCEC

Registry ID

RPCEC00000081

Enrollment

221

Registered

2009-07-03

Start date

2006-09-17

Completion date

Unknown

Last updated

2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Pterygium

Interventions

Group I: pterygium excision or pterigiectomy plus Amniotic Membrane Transplantation Group II: pterygium excision or pterigiectomy plus Conjunctival–Limbal Autograft

Eligibility

Sex/Gender

All

Age

15 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with primary pterigium grade II or higher. Cubans. Over 15 years of age.

Exclusion criteria

Exclusion criteria: With recurrent pterigium of any grade Previous corneal perforation or perforating trauma. Suspected conjunctival malignancy. Corneal leucoma. Any corneal inflammatory or degenerative disease. Background of allergy to topic steroids or Sjögren syndrome. If a patient presents pterigium in both eyes, only the worst eye will be included.

Design outcomes

Primary

Measure	Time frame
Recurrence onset during first 6 months after surgery.	—

Secondary

Measure	Time frame
Complications during first 6 months and one year after surgery. Difference between visual acuity before and after surgery (6 months and one year) Ametropy status compared with preoperative status (6 months and one year). Time to recurrence. Esthetic Appearance (6 months and one year).	—

Countries

Cuba

Contacts

Public ContactBelmary Aragonés

“Hermanos Ameijeiras” General Hospital

belmaryc@infomed.sld.cu

Outcome results

None listed

Source: RPCEC (via WHO ICTRP) · Data processed: Aug 15, 2026